Home / GATE 2017-2018 / GATE Biotechnology :: Practice Test Paper 1

GATE 2017-2018 :: GATE Biotechnology

  1. Synteny refers to
  2. A.
    gene duplication from a common ancestor
    B.
    a tree representation of related sequences
    C.
    the extent of similarity between two sequences
    D.
    local conservation of gene order

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  3. While searching a database for similar sequences, E value does NOT depend on the
  4. A.
    sequence length
    B.
    number of sequences in the database
    C.
    scoring system
    D.
    probability from a normal distribution

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  5. In transmission electron microscopy, electron opacity is greatly enhanced by treating the specimen with
  6. A.
    ferrous ammonium sulfate
    B.
    uranium acetate
    C.
    sodium chloride
    D.
    basic fuchsin

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  7. The molarity of water in a water : ethanol mixture (15 : 85, v/v) is approximately
  8. A.
    0.85
    B.
    5.55
    C.
    8.5
    D.
    55.5

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  9. The helix content of a protein can be determined using
  10. A.
    an infrared spectrometer
    B.
    a fluorescence spectrometer
    C.
    a circular dichroism spectrometer
    D.
    a UV-Visible spectrophotometer

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  11. Which one of the following DNA sequences carries an invert repeat?
  12. A.
    ATGAGCCCCGAGTA 
    TACTCGGGGCTCAT
    B.
    ATGAGCCGGCTCTA 
    TACTCGGCCGAGAT
    C.
    ATGAGCCGAGCCTA 
    ACTCGGCTCGGAT
    D.
    ATGAGCCTATGGTA 
    TACTCGGATACCAT

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  13. In zinc finger proteins, the amino acid residues that coordinate zinc are
  14. A.
    Cys and His
    B.
    Asp and Glu
    C.
    Arg and Lys
    D.
    Asp and Arg

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  15. Match the entries in Group I with those in Group II.
    Group I                  Group II
    P. MTT                 1. Dihydrofolate reductase
    Q. Annexin V       2. Succinate dehydrogenase
    R. Methotrexate  3. Microtubules
    S. Taxol                 4. Phosphatidylserine
  16. A.
    P-3, Q-1, R-4, S-2
    B.
    P-2, Q-4, R-1, S-3
    C.
    P-2, Q-3, R-4, S-1
    D.
    P-4, Q-2, R-1, S-3

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  17. In an exponentially growing batch culture of Saccharomyces cerevisiae, the cell density is 20 gl-1 (DCW), the specific growth rate (μ) is 0.4 h-1 and substrate uptake rate (v) is 16 gl-1h-1. The cell yield coefficient Yx/s will be
  18. A.
    0.32
    B.
    0.64
    C.
    0.80
    D.
    0.50

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  19. A single base pair of DNA weighs 1.1 * 10-21 grams. How many picomoles of a plasmid vector of length 2750 bp are contained in 1 μg of purified DNA?
  20. A.
    0.30
    B.
    0.55
    C.
    0.25
    D.
    0.91

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